Author

James C. Bowden

California Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Frances H. ArnoldiD· 1 shared Jason YangiD· 1 shared Matthew Hill· 1 shared Mikhail A. HameediiD· 1 shared Raul AstudilloiD· 1 shared Ravi G. LaliD· 1 shared Sukhvinder KauriD· 1 shared Yisong YueiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBioengineering

Frances H. ArnoldORCID

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1 paper

Recent·Most cited

Active Learning-Assisted Directed Evolution

Jason Yang, Ravi G. Lal, James C. Bowden, Raul Astudillo, Mikhail A. Hameedi, Sukhvinder Kaur, Matthew Hill, Yisong Yue, Frances H. Arnold

This paper introduces ALDE, a machine learning-assisted directed evolution method that improves protein engineering outcomes by efficiently exploring epistatic mutation spaces.

Nature Communications · Jan 16, 2025Peer-reviewedBioengineering