Author

Ravi G. Lal

California Institute of TechnologyORCID 0000-0001-6943-4147Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ravi G. Lal1 paper · California Institute of Technology

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Amanda C. HernándeziD· 1 shared Amin Zargar· 1 shared Andrew R. Wong· 1 shared Edward E. K. BaidooiD· 1 shared Frances H. ArnoldiD· 1 shared James C. Bowden· 1 shared Jason YangiD· 1 shared Jay D. KeaslingiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Amanda C. HernándezORCID

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2 papers

Recent·Most cited

BioengineeringNature CommunicationsPeer-reviewedJan 16, 2025

Active Learning-Assisted Directed Evolution

Jason Yang, Ravi G. Lal, James C. Bowden…·Frances H. Arnold

This paper introduces ALDE, a machine learning-assisted directed evolution method that improves protein engineering outcomes by efficiently exploring epistatic mutation spaces.

165 citationstop 1%

protein sequencedeep learning

𝕏 PostBluesky

Synthetic BiologyMetabolic EngineeringPeer-reviewedSep 1, 2020

A bimodular PKS platform that expands the biological design space

Amin Zargar, Luis E. Valencia, Jessica C Wang…·Jay D. Keasling

The paper engineers bimodular PKS systems to produce unnatural polyketides as bio-based chemicals, demonstrating both successes and challenges in product fidelity.

9 citations

experimental assay

𝕏 PostBluesky