CIZ1 regulates G1 length and the CDK threshold for initiation of DNA replication to prevent DNA replication stress
James Tollitt, Marcus K Preedy, Tiernan Briggs, Sarah L. Allinson, Christopher J. Staples, Jason Luke Parsons, Richard L. Mort, Nikki A. Copeland
This study shows that CIZ1 regulates G1 length and the CDK threshold for DNA replication initiation, preventing DNA replication stress and genome instability.
Nucleic Acids Research · Sep 4, 2026Peer-reviewedCell Biology