Population genetics meets precision-cut kidney slices: Nephrotoxicity modelled ex vivo in the founder strains of the BXD mouse consortium
Jana Andres, Nichakorn Phengpol, Mikhail Burmakin, Hannes Olauson, Jaakko Patrakka, Matthias B. Moor
The paper uses precision-cut kidney slices from BXD mouse strains to model nephrotoxicity ex vivo, finding strain-specific differences in susceptibility to drug-induced kidney injury.
bioRxiv · Jun 21, 2026 · PreprintPharmacology & Toxicology