Comparison of one-stage and two-stage genome-wide association studies
Shang Xue, Funda Ogut, Zachary R. Miller, Janu Verma, Peter J. Bradbury, James Brendan Holland
This study compares one-stage and two-stage GWAS methods, finding that a weighted two-stage approach reduces bias and improves power, especially in unbalanced data.
bioRxiv · Jan 9, 2017 · PreprintGenetics