Rebecca S Bart

The paper tests two CRISPR-based epigenome editing tools in cassava to induce DNA methylation at susceptibility gene promoters, reducing pathogen infection and showing inheritance patterns.

The paper uses CRISPR interference to methylate promoters of eIF4E genes in cassava, reducing gene expression and disease susceptibility.

The paper identifies mutations in cassava eIF4E-family genes that reduce CBSD symptoms by disrupting VPg interaction, suggesting potential strategies for disease resistance.

The paper improves signal-to-noise ratios in field trials by using spatial principal component regression to control for soil property effects on plant traits and microbiomes.

The paper assembles and resolves two haplotypes of a cassava line using multiple sequencing technologies, revealing over 5,000 large structural variants.

The paper constructs a cassava haplotype map to evaluate deleterious mutations, finding increased fixed deleterious variants, limited purging due to low recombination, and masking of harmful mutations in breeding.