Genetic & Genomic MedicinemedRxivPreprint
Sex-related signatures in the plasma proteome not attributable to XX and XY chromosomes and their impact on health and disease
Essi Viippola, Tuomo Hartonen, Meihui Zhu…·Andrea Ganna
The paper introduces the Proteomic Sex Index (PSI), a continuous measure of plasma proteome alignment with chromosomal sex, showing its association with health and disease traits.
DOI 10.64898/2026.10.19.26365875