Ryuya Edahiro

The paper introduces the Proteomic Sex Index (PSI), a continuous measure of plasma proteome alignment with chromosomal sex, showing its association with health and disease traits.

The paper performs a federated cis-eQTL meta-analysis across single-cell datasets to identify cell-type-specific genetic effects and link them to disease mechanisms.

This study performs a genome-wide association study for Long COVID, identifying a significant association with the FOXP4 locus and highlighting the role of pulmonary dysfunction and COVID-19 severity.

This study identifies the Rubicon-WIPI axis as a regulator of exosome biogenesis, showing its role in age-dependent exosome release and microRNA fate in mice.

The paper introduces scLinaX, a method to quantify X chromosome inactivation escape using scRNA-seq, revealing heterogeneity across cell types and tissues.

The paper reports a genome-wide association study of COVID-19 in a Japanese population, identifying a novel risk variant associated with severe disease in younger patients.