Single cell functional immunogenomics of the fallopian tube reveals a precursor immune surveillance network for ovarian cancer prevention
Luyao Wang, Breeshey Roskams-Hieter, Nosheen Hussain, Joel Nulsen, Aneesh Aggarwal, May Sallam, Lili Wang, Lena J. Rai, Amro Ahmed-Ebbiary, Aws Al-Deka, Takashi Takeda, Mara Artibani, Hooman Soleymani majd, Jason Yap, Christopher Yau, , Ahmed A. Ahmed
The paper uses single-cell sequencing to show that immune cells in the fallopian tube share clonotypes with ovarian cancer tumors, suggesting a role in early immune surveillance.
bioRxiv · Jun 30, 2025 · PreprintImmunology