Author
Health Data Research UKORCID 0000-0002-1119-2576Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Joshua Slaughter, Olivier Labayle, Breeshey Roskams-Hieter…·Chris Paul Ponting
Targeted-learning GWAS of 1,268 UK Biobank ME/CFS cases found 176 FDR-significant variants; seven replicated in disjoint UK Biobank or All of Us cohorts.
Breeshey Roskams-Hieter, Øyvind Almelid, Chris Paul Ponting
The paper identifies 1,960 variants that disrupt transcription factor binding affinity by analyzing ChIP-sequencing data for allelic imbalance at heterozygous sites.
Breeshey Roskams-Hieter, Olivier Labayle, Kelsey Tetley-Campbell…·Ava Khamseh
The paper identifies epistatic interactions among DNA variants affecting human traits by combining machine learning with experimentally verified transcription factor binding data.
Luyao Wang, Breeshey Roskams-Hieter, Nosheen Hussain…·Ahmed A. Ahmed
The paper uses single-cell sequencing to show that immune cells in the fallopian tube share clonotypes with ovarian cancer tumors, suggesting a role in early immune surveillance.
Hyun Ji Kim, Matthew J. Rames, Florian Goncalves…·Thuy T. M. Ngo
The paper analyzes cf-mRNA in EVs and non-vesicular carriers from cancer patients and healthy donors, finding EVs selectively enrich cf-mRNA associated with specific biological pathways.