The effect of dipeptide repeat proteins on FUS/TDP43-RNA condensation in C9orf72 ALS/FTD
Mark D. Driver, Jasper Postema, Patrick R. Onck
This study investigates how dipeptide repeat proteins (DPRs) affect FUS/TDP43-RNA condensation in ALS/FTD, showing that R-DPRs disrupt condensates through cation-{pi} and electrostatic interactions.
The Journal of Physical Chemistry B · Sep 23, 2024Peer-reviewedBiophysics