Agonism of mosquito and human transient receptor potential ankyrin 1 (TRPA1) channels by the natural drimane sesquiterpene cinnamodial
Tae Lee, Jayce Liu, Yeaeun Park, H. Liva Rakotondraibe, Xiaolin Cheng, Peter M. Piermarini
This paper investigates the agonism of mosquito and human TRPA1 channels by cinnamodial, comparing its potency and selectivity to other agonists and identifying potential binding sites.
bioRxiv · Dec 11, 2025 · PreprintPharmacology & Toxicology