The pan-cancer whole-genome landscape of Adolescent and Young Adult solid cancers
Jeffrey van Putten, Axel Rosendahl Huber, Roelof Koster, Sophie Roerink, Joep de Ligt, Paul Roepman, Sjors M. Kas, Ruben van Boxtel, Winette van der Graaf, Edwin P. J. G. Cuppen, Hilde H. Nienhuis
This study compares whole-genome sequences of adolescent and young adult solid cancers to older adult cancers, finding shared genetic drivers but age-related differences in mutational processes and germline variants.
bioRxiv · Oct 16, 2026 · PreprintCancer Biology