Gene-drug interactions identify genomic loci that enhance statin effectiveness in lowering LDL cholesterol.
Brad Verhulst, Jennifer Harris, Amy M. Adams, Sarah E. Benstock, Carl Wei-Chan Tong, Adam John Case, John M. Hettema
The paper identifies gene-statin interactions that enhance statin effectiveness in lowering LDL cholesterol using genome-wide analyses in the UK Biobank and All of Us.
bioRxiv · Feb 6, 2026 · PreprintGenetics