Delivery of BACE1 siRNA mediated by TARBP-BTP fusion protein reduces β-amyloid deposits in a transgenic mouse model of Alzheimers disease
Mohamed Mohamed Haroon, Kamal Saba, Venkata Harsha Vardhan Boddeda, Jerald Mahesh Kumar, Anant Bahadur Patel, Vijaya Gopal
This study demonstrates that TARBP-BTP fusion protein-mediated delivery of BACE1 siRNA reduces β-amyloid deposits and improves cognitive function in a transgenic Alzheimer's disease mouse model.
Journal of Biosciences · Jan 30, 2019Peer-reviewedNeuroscience