Demographic and immune-based selection shifts before and after European contact inferred from 50 ancient and modern exomes from the Northwest Coast of North America
John Lindo, Emilia Huerta-Sánchez, Shigeki Nakagome, Morten Rasmussen, Barbara Petzelt, Joycellyn Mitchell, Jerome S Cybulski, Eske Willerslev, Michael DeGiorgio, Ripan S Malhi
The paper analyzes 50 ancient and modern exomes from the Northwest Coast of North America to infer demographic and immune-based selection shifts before and after European contact, finding a population size reduction and selection pressure changes on immune genes.
bioRxiv · Apr 29, 2016 · PreprintGenetics