Author

Shigeki Nakagome

Primary ORCID profile (0000-0001-9613-975X · 6 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Shigeki NakagomeiD6 papers · Trinity College Dublin

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Anna Di Rienzo· 1 shared Barbara Petzelt· 1 shared David B Witonsky· 1 shared Emilia Huerta-Sánchez· 1 shared Eske Willerslev· 1 shared Jerome S Cybulski· 1 shared John D Blischak· 1 shared John Lindo· 1 shared

Activity by Year

2015-2016 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Anna Di Rienzo

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2 papers

Recent·Most cited

Demographic and immune-based selection shifts before and after European contact inferred from 50 ancient and modern exomes from the Northwest Coast of North America

John Lindo, Emilia Huerta-Sánchez, Shigeki Nakagome, Morten Rasmussen, Barbara Petzelt, Joycellyn Mitchell, Jerome S Cybulski, Eske Willerslev, Michael DeGiorgio, Ripan S Malhi

The paper analyzes 50 ancient and modern exomes from the Northwest Coast of North America to infer demographic and immune-based selection shifts before and after European contact, finding a population size reduction and selection pressure changes on immune genes.

bioRxiv · Apr 29, 2016 · PreprintGenetics

Patterns of transcriptional response to 1,25-dihydroxyvitamin D3 and bacterial lipopolysaccharide in primary human monocytes

Silvia N Kariuki, John D Blischak, Shigeki Nakagome, David B Witonsky, Anna Di Rienzo

This study examines the transcriptional response of human monocytes to 1,25D and LPS, identifying gene expression patterns and pathways involved in immunomodulation and ethnic differences.

bioRxiv · Nov 6, 2015Genetics