Single-molecule tracking of RNA-DNA hybrid removal enzymes important for lagging-strand replication
Daniel J. Foust, Frances Caroline Lowder, Jessica Chung, Julianna R. Cresti, Lieke A. van Gijtenbeek, Lyle A. Simmons, Julie S. Biteen
This study uses single-molecule tracking to analyze the behavior of three proteins involved in removing RNA-DNA hybrids during lagging-strand replication in Bacillus subtilis, revealing their dynamic interactions with the replisome and nucleoid.
Biophysical Journal · Jun 12, 2026Peer-reviewedBiophysics