Study of Principles Governing Epithelial Cell Clustering and Collective Motion In Vitro
Jia Gou, Mykhailo Potomkin, Jonard P Ingal, Sergei Butenko, Wendy F. Liu, Maksim V. Plikus, Mark Alber
This paper develops a computational model to study how cell size, polarity, and adhesion influence collective migration of epithelial cells in vitro, showing that mixed-size clusters can exhibit straight translation or rotation based on biomechanical interactions.
bioRxiv · Jul 30, 2026 · PreprintCell Biology