Mark Alber

This paper develops a computational model to study how cell size, polarity, and adhesion influence collective migration of epithelial cells in vitro, showing that mixed-size clusters can exhibit straight translation or rotation based on biomechanical interactions.

This study analyzes two aging modes in yeast, showing spherical budding cells better control growth and size, and develops a model to test mechanisms of bud morphogenesis during aging.

The paper investigates how cytoskeletal regulation and proliferation are coordinated during Drosophila wing disc development to balance tissue growth and shape.

The paper develops a multiscale chemical-mechanical model to study how the spatial distribution of the Dpp morphogen affects tissue growth in Drosophila wing discs, showing that a larger gradient domain leads to increased size, faster growth, and more symmetric shape.

The paper predicts enzyme regulation policies using statistical thermodynamics and hybrid optimization-reinforcement learning to maintain solvent capacity in E. coli central metabolism.