Iron promotes Slc7a11-deficient valvular interstitial cell osteogenic differentiation: A possible mechanism by which ferroptosis participates in intraleaflet hemorrhage-induced calcification.
Ran Xu, Ying Huang, Dan Zhu, Jianghong Guo
This paper investigates how iron promotes osteogenic differentiation of Slc7a11-deficient valvular interstitial cells through ferroptosis, contributing to aortic valve calcification.
Free Radical Biology and Medicine · Mar 21, 2022Peer-reviewedMolecular Biology