A Multimodal Deep Learning Framework for Predicting PPI-Modulator Interactions
Heqi Sun, Jianmin Wang, Hongyan Wu, S L Lin, Junwei Chen, Jinghua Wei, Shuai Lv, Yi Xiong, Dong-Qing Wei
This paper introduces MultiPPIMI, a deep learning framework that predicts PPI-modulator interactions without requiring target structure or reference modulators, achieving high AUROC scores in benchmark tests.
Journal of Chemical Information and Modeling · Dec 1, 2023Peer-reviewedBioinformatics