Construction of a GnRH mRNA Immunocastration Vaccine and Evaluation of Its Immunogenicity and Safety in Mice and Cats
Y. Chen, Chao Dong, Wenqian Yan, Yakun Liu, Jixiang Sun, Mingshuo Ji, Jiahan Gang, Jiaqi Nie, Xinhao Zhang, He Huang, Yongfei Zhou
This paper develops a GnRH mRNA vaccine using pLS nanoparticles and evaluates its immunogenicity, reproductive suppression, and safety in mice and cats.
bioRxiv · Mar 26, 2026 · PreprintImmunology