Integration of early-stage cryopreservation and cell cycle modulation into a flexible kidney organoid differentiation system
Xiaotian Yan, Jina Wang, Ming Xu, Chunlan Hu, Siyue Chen, Yufeng Zhao, Jiyan Wang, Ruiming Rong, Tongyu Zhu, Weitao Zhang
This paper develops a method to pause and resume kidney organoid differentiation using cryopreservation and cell cycle modulation, enabling scalable and reproducible organoid research.
bioRxiv · Jan 16, 2026 · PreprintDevelopmental Biology