TRIO-AI: Hybrid temporal graph, ODE, and VAE modeling for high-resolution cellular trajectory inference in liver injury
hui li, jinlian Wang, Yankai Wen, Hongfang Liu, Cynthia Ju
TRIO-AI identifies a transitional macrophage population in liver injury using a hybrid model of temporal graphs, ODEs, and VAEs, revealing key signaling pathways and spatial localization.
bioRxiv · Dec 19, 2025 · PreprintBioinformatics