Lymph Node Dissection and Radiation in the Rat Popliteal Region Leads to Progressive Lymphatic Pump Failure and Lymphedema
Shao‐Yun Hsu, Young Jae Ryu, Zhanna V. Nepiyushchikh, Kiyoung Jeong, Jinseo Yu, J. Brandon Dixon
This study uses a rat model to show that lymphatic pump failure leads to lymphedema, with functional and structural changes confirmed by volumetry and NIR imaging.
bioRxiv · Mar 14, 2026 · PreprintBioinformatics