Length-dependent translation efficiency of ER-destined proteins
Hana Sahinbegovic, Alexander Vdovin, Renáta Šnaurová, Michal Ďurech, Jakub Nezval, Jiri Sobotka, Roman Hájek, Tomáš Jelı́nek, Michal Šimíček
The paper shows that long ER-targeted mRNAs are translated while bound to the ER, whereas short mRNAs repeatedly pause, leading to lower translation efficiency for small ER-targeted proteins.
Current Issues in Molecular Biology · Aug 14, 2023Peer-reviewedMolecular Biology