Tox21mer, A transformer foundation model for Tox21 high-throughput concentration-response curves data
Leping Li, Jisoo Hwang, Keith R. Shockley, YuanYuan Li, Alison A. Motsinger‐Reif, Jui‐Hua Hsieh, Scott S. Auerbach, David M. Reif
Tox21mer is a transformer model trained on Tox21 concentration-response curves to predict compound activity and AC50, achieving high accuracy in outcome prediction and log10(AC50) estimation.
bioRxiv · Jun 19, 2026 · PreprintBioinformatics