Highly Stable Mn(V)-Nitrido and Nitrogen-Atom Transfer Reactivity within a De Novo Protein
Jithin Thomas, Sudha Yadav, Paul H. Oyala, Veronica Carta, Alec H. Follmer, David Philip Goldberg, Samuel I. Mann
This paper designs a de novo protein to stabilize a Mn(V)-nitrido complex and demonstrates its use in enantioselective aziridination with high turnover and enantiomeric ratio.
Journal of the American Chemical Society · Jun 3, 2026Peer-reviewedBiochemistry