Tracing Endometriosis: Coupling deeply phenotyped, single-cell based Endometrial Differences and AI for disease pathology and prediction
Lea Duempelmann, Shaoline Sheppard, Angelo Duò, Jitka Skrabalova, Brett David McKinnon, Thomas Andrieu, Dennis Goehlsdorf, Sukalp Muzumdar, Cinzia Donato, Ryan Lusby, Wiebke Solaß, Hans C. Bösmüller, Peter Nestorov, Michael D. Mueller
The paper creates a large single-cell endometrial atlas and uses AI to identify gene expression and receptor-ligand changes associated with endometriosis, developing predictive models for disease severity.
bioRxiv · Aug 9, 2024 · PreprintMolecular Biology