De novo design of a safe and potent respiratory syncytial virus immuno-focusing antigen
Woo Yeon Hwang, Jinung Song, Jiwon Choe, Keun Bon Ku, Hyung-Sun Kim, Gun Young Yoon, Do Yeon Kim, Mi‐Ra Choi, Eun‐Ji Kim, Jae Seung Lee, SungJun Park, Sung Kyun Lee, Seung Jun Kim, Bonsu Ku, Dae‐Gyun Ahn, , Young‐Chan Kwon
This study designs a de novo RSV antigen using AI to reduce immunopathology while maintaining immunogenicity, showing safety and efficacy in preclinical models.
bioRxiv · Jan 29, 2026 · PreprintMicrobiology