Conditional U1 Gene Silencing in Toxoplasma gondii
Manuela S Pieperhoff, Gurman S Pall, Elena Jimenez-Ruis, Sujaan Das, Eleanor H Wong, Joanne Heng, Sylke Mueller, Michael J Blackman, Markus Meissner
This paper introduces a new gene silencing method in Toxoplasma gondii using U1 snRNP-mediated cleavage, enabling conditional knockdown of target genes for functional studies.
PLOS ONE · Jun 19, 2015Peer-reviewedMolecular Biology