SOX9 regulates endothelial tip cell specification to promote cerebral and neuroretinal vascularization
Typhaine Anquetil, Gaël Cagnone, joel howard, Lily Kennepohl, Sahily Rodriguez-Torres, Bruno Larrivée, Alexandre Dubrac
This study identifies SOX9 as a regulator of endothelial tip cell specification in brain and retinal vascularization, showing its role in promoting angiogenesis and revealing differences between developmental and injury-induced vascular responses.
bioRxiv · Jun 9, 2026 · PreprintDevelopmental Biology