Alexandre Dubrac

This study identifies SOX9 as a regulator of endothelial tip cell specification in brain and retinal vascularization, showing its role in promoting angiogenesis and revealing differences between developmental and injury-induced vascular responses.

This study identifies a novel angiogenic endothelial cluster driven by loss of ALK1 signaling in brain arteriovenous malformations (bAVMs) and shows that KIT inhibition prevents bAVM formation.