Intracellular competitions reveal the combination of active partitioning and addiction mechanisms as most advantageous for low-copy plasmid fitness
Johannes Effe, Mario Santer, Yiqing Wang, Theresa E. Feenstra, Nils F. Hülter, Tal Dagan
The paper compares plasmid persistence strategies and finds that combining active partitioning with toxin-antitoxin systems maximizes plasmid fitness in prokaryotes.
bioRxiv · Feb 11, 2025 · PreprintMicrobiology