Controlling noise in the timing of intracellular events: A first-passage time approach
Khem Raj Ghusinga, John J Dennehy, Abhyudai Singh
The paper uses a first-passage time framework to analyze how feedback regulation affects the precision of intracellular event timing, finding that constant expression is optimal for stable proteins while positive feedback improves timing for unstable ones.
Proceedings of the National Academy of Sciences · Jan 9, 2017Peer-reviewedBiophysics