Genetically encoded RNA strand exchange circuits for programmable protein expression and computation in cells
Samuel W. Schaffter, Olga B Vasilyeva, Molly Wintenberg, John M Hurley, Nina Alperovich
This study demonstrates genetically encoded RNA strand exchange circuits in living cells, showing that in vitro TMSE design principles apply to E. coli but with cellular-specific caveats.
bioRxiv · Sep 24, 2025 · PreprintSynthetic Biology