GenomicsbioRxivPreprint
DNA methylation landscapes of matched primary and recurrent high grade serous ovarian cancers are preserved throughout disease progression and chemoresistance.
Nicole Gull, Michelle R. Jones, Pei-Chen Peng…·Simon A. Gayther
This study shows that DNA methylation and gene expression patterns are preserved in recurrent high grade serous ovarian cancers, with BRCA1/2 carriers showing more shared methylation changes and improved survival.
2 citations