B.J. Rimel

This study profiles the proteome of ovarian cancer tumors before and after chemotherapy, revealing how HRD status affects immune pathways and identifies potential therapeutic targets.

This study shows that mutational and clonality profiles in HGSOC are established early and remain stable through therapy resistance.

This study uses single-cell transcriptomics to identify gene expression networks in the human fallopian tube, revealing epithelial subtypes and their role in cancer progression.

This study shows that DNA methylation and gene expression patterns are preserved in recurrent high grade serous ovarian cancers, with BRCA1/2 carriers showing more shared methylation changes and improved survival.