upSPLAT: Early-Barcoded Library Preparation for Cost-Effective Population-Scale Genomics
Amanda Raine, Ryan J. Daniels, Jonas Kjellin, Ann-Christin Wiman, Ulrika Liljedahl, Jon Ramsell, Christopher West Wheat, Karl Gotthard, Mats E. Pettersson, L I Andersson, Jessica Nordlund
upSPLAT reduces library preparation costs by 10-fold through early barcoding and single-stranded ligation, enabling cost-effective, high-plex sequencing across diverse DNA inputs.
bioRxiv · May 13, 2026 · PreprintGenomics