Author

Jonas Lindner

Technical University of Munich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Florian R. HölzlwimmeriD· 2 shared Francesco Paolo CasaleiD· 2 shared Julien GagneuriD· 2 shared Eva HoltkampiD· 1 shared Felix BrechtmanniD· 1 shared Nils WagneriD· 1 shared Shubhankar LondheiD· 1 shared Vicente A. YépeziD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersGenetics

Florian R. HölzlwimmerORCID

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2 papers

Recent·Most cited

Functional gene embeddings improve rare variant polygenic risk scores

Shubhankar Londhe, Jonas Lindner, Zhifen Chen, Eva Holtkamp, Florian R. Hölzlwimmer, Francesco Paolo Casale, Felix Brechtmann, Julien Gagneur

FuncRVP improves rare variant polygenic risk scores by integrating functional gene embeddings, enhancing performance for traits with higher heritability.

bioRxiv · Jul 22, 2024 · PreprintGenetics

Aberrant expression prediction across human tissues

Florian R. Hölzlwimmer, Jonas Lindner, Nils Wagner, Francesco Paolo Casale, Vicente A. Yépez, Julien Gagneur

The paper develops AbExp, a model predicting aberrant gene expression across tissues, achieving 12% average precision by integrating variant effects and tissue-specific expression variability.

bioRxiv · Dec 4, 2023 · PreprintGenetics