Elucidating a potential role of the infant gut microbiome on the bioavailability of L-tyrosine in phenylketonuria
Mohammadreza Moghimi, Filippo Martinelli, Jonas Widder, Tim Hensen, Luciana Hannibal, Ute Spiekerkoetter, Ines Thiele
The paper uses metabolic models to show that gut microbiome composition affects L-tyrosine availability in PKU, suggesting microbiome-targeted therapies.
bioRxiv · Oct 28, 2025 · PreprintSystems Biology