Author

Jonathan Kropski

Vanderbilt University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jens MeileriD· 1 shared John A. CapraiD· 1 shared John Phillips· 1 shared Jonathan Sheehan· 1 shared Joy Cogan· 1 shared R. Michael SivleyiD· 1 shared Timothy S. BlackwelliD· 1 shared William S. BushiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Jens MeilerORCID

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1 paper

Recent·Most cited

Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures

R. Michael Sivley, Jonathan Kropski, Jonathan Sheehan, Joy Cogan, Xiaoyi Dou, Timothy S. Blackwell, John Phillips, Jens Meiler, William S. Bush, John A. Capra

The paper analyzes the spatial distribution of missense variants in human protein structures to classify variants of unknown significance, finding disease-causing variants cluster more than benign ones.

The American Journal of Human Genetics · Feb 15, 2018Peer-reviewedGenetics