Author

Xiaoyi Dou

Vanderbilt UniversityORCID 0000-0003-2502-6154Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jens MeileriD· 1 shared John A. CapraiD· 1 shared John Phillips· 1 shared Jonathan Kropski· 1 shared Jonathan Sheehan· 1 shared Joy Cogan· 1 shared R. Michael SivleyiD· 1 shared Timothy S. BlackwelliD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Jens MeilerORCID

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1 paper

Recent·Most cited

GeneticsThe American Journal of Human GeneticsPeer-reviewedFeb 15, 2018

Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures

R. Michael Sivley, Jonathan Kropski, Jonathan Sheehan…·John A. Capra

The paper analyzes the spatial distribution of missense variants in human protein structures to classify variants of unknown significance, finding disease-causing variants cluster more than benign ones.

79 citationstop 3%

humanprotein structure

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