OBESITY-INDUCED ENDOTHELIAL FENESTRATION AND CAPILLARY LEAKAGE CONTRIBUTE TO INCREASED PAIN SENSATION
Yuta Koui, Jonathan Richard Shin, Shuxuan Song, Christian A. Combs, Yoh‐suke Mukouyama
The paper shows obesity causes capillary leakage in skin, leading to NGF production and pain hypersensitivity, suggesting capillary permeability as a therapeutic target.
bioRxiv · Mar 16, 2026 · PreprintNeuroscience