Flux estimation analysis systematically characterizes the metabolic shifts of the central metabolism pathway in human cancer.
Grace Meijuan Yang, Shaoyang Huang, Kevin Hu, Alex Z Lu, Jonathan Yang, Noah Meroueh, Pengtao Dang, Yijie Wang, Haiqi Zhu, Sha Cao, Chi Zhang
This study uses TCGA transcriptomics data to analyze metabolic shifts in 11 cancer subtypes and their adjacent normal tissues, revealing patterns in glucose uptake, glycolysis, TCA cycle, and glutaminolysis.
Frontiers in Oncology · Jun 12, 2023Peer-reviewedBioinformatics