BioinformaticsFrontiers in OncologyPeer-reviewed
Flux estimation analysis systematically characterizes the metabolic shifts of the central metabolism pathway in human cancer.
Grace Meijuan Yang, Shaoyang Huang, Kevin Hu…·Chi Zhang
This study uses TCGA transcriptomics data to analyze metabolic shifts in 11 cancer subtypes and their adjacent normal tissues, revealing patterns in glucose uptake, glycolysis, TCA cycle, and glutaminolysis.
DOI 10.3389/fonc.2023.1117810