Combinatorial Treatment Increases IKAP Levels in Human Cells Generated from Familial Dysautonomia Patients
Sivan Yannai, Jonathan Zonszain, Maya Donyo, Gil Ast
The paper shows that combining PS with kinetin or TSA increases IKAP levels in FD patient-derived cells, suggesting different pathways, while pridopidine adds to these effects but not with PS, indicating shared mechanisms.
PLoS ONE · Mar 19, 2019Peer-reviewedMolecular Biology