High-throughput Image-based Clustering of CAR-T/Tumor Cocultures for Rapid and Facile Hit Identification
Zhi Xu, Xueqi Liu, Kirby Madden-Hennessey, Jordan Urbani, Shahryar Khoshtinat Nikkhoi, Anusuya M. Ramasubramanian, Kartika Venugopal, Qi Zhao, Eric L. Smith, Yun Fu
This paper introduces a novel image clustering approach for CAR-T/tumor cocultures using U-net and clustering algorithms, demonstrating superior performance in classification and data interpretation.
bioRxiv · Aug 28, 2024 · PreprintCell Biology