Author

Jorge Armando Verduzco-Martínez

Universidad Autónoma de Nuevo León

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Systems Biology· 1

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Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

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Elena R Alvarez-BuyllaiD· 1 shared José Dávila-VelderrainiD· 1 shared José Luis Caldú-PrimoiD· 1 shared

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2021-2021 · peak 1/yr

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Elena R Alvarez-BuyllaORCID

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Systems BiologyNAR Genomics and BioinformaticsPeer-reviewedJun 23, 2021

In vivo and in vitro human gene essentiality estimations capture contrasting functional constraints

José Luis Caldú-Primo, Jorge Armando Verduzco-Martínez, Elena R Alvarez-Buylla, José Dávila-Velderrain

The paper compares in vivo and in vitro gene essentiality estimates to assess functional constraints and identifies genes with contrasting mutational tolerance.

2 citations

humanwhole-exome sequencing

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